Weed and Grass Killer

Weed and Grass Killer

Shop selective and non-selective herbicides for clearing weeds, unwanted grass and overgrown areas around lawns, driveways, fence lines and landscapes.

When you need to completely remove unwanted weeds, grass or overgrown vegetation, a professional-grade weed and grass killer gives you the control needed to start clean. This collection includes non-selective herbicides such as Roundup QuikPRO and LESCO Prosecutor Pro for spot treatments, landscape beds, fence lines, driveways and complete lawn renovation.

These products are designed to kill nearly any actively growing plant they contact. That makes them highly effective, but careful application is essential. A grass and weed killer should never be sprayed over a lawn, shrub or ornamental plant you want to keep.

Professional Weed and Grass Killers

Unlike a selective weed killer for grass, the products in this collection are non-selective. They control both broadleaf weeds and unwanted grasses, including difficult grassy weeds and established turf.

Use them when the goal is to eliminate all vegetation in a specific area—not when you only want to remove weeds from an otherwise healthy lawn.

Best Uses

  • Spot spraying weeds and unwanted grass in landscape beds
  • Controlling vegetation along fences, walkways and driveways
  • Cleaning up weeds around buildings and other non-crop areas
  • Killing unwanted turf before repairing or renovating a lawn
  • Removing bermudagrass or other invasive grass from selected areas

How Glyphosate Weed and Grass Killer Works

Glyphosate is a systemic, non-selective herbicide. It is absorbed through actively growing leaves and other green plant tissue, then moves throughout the plant to control both the visible growth and underground plant parts.

Glyphosate products such as LESCO Prosecutor Pro have no soil activity. They control vegetation that is actively growing when sprayed, but they do not prevent new weeds from germinating later. Grass seed placed into the soil is not controlled simply because glyphosate was previously sprayed over the area.

For the best control, allow the treated grass or weeds enough time to absorb and move the herbicide before mowing, tilling, dethatching or disturbing the soil. When renovating turf, always follow the waiting period and reseeding directions stated on the specific product label.

Spot Spraying Around Landscapes

A grass and weed killer can be used to carefully spot spray unwanted vegetation growing near shrubs, trees and ornamental beds. Spraying beside a desirable plant is acceptable when the application is directed only at the weed and the spray does not contact the desirable plant.

Do not allow the spray to touch green bark, leaves, exposed roots, shoots or other actively growing parts of shrubs, flowers or trees. Even a small amount of spray drift can cause discoloration, injury or complete plant death.

Apply Carefully

  • Spray only when the air is calm and wind is minimal.
  • Use a coarse, controlled spray rather than a fine mist.
  • Keep the spray nozzle close to the target vegetation.
  • Avoid spraying desirable plants, exposed roots and green stems.
  • Do not spray foliage to the point of dripping or runoff.
  • Check the forecast and follow the product's rainfast period.

Heavy rain shortly after application can wash herbicide from the foliage and reduce control. Wind and poorly controlled spray droplets can also carry the herbicide into areas you did not intend to treat. Always read and follow the complete product label before mixing or applying any herbicide.

Choose the Right Grass and Weed Killer

Roundup QuikPRO

Roundup QuikPRO combines glyphosate with diquat for fast visible results and systemic control. It is a strong choice for customers who want a fast-acting weed and grass killer for spot treatments, edging and vegetation cleanup.

LESCO Prosecutor Pro

LESCO Prosecutor Pro is a concentrated glyphosate herbicide for systemic control of emerged weeds, unwanted grasses and other vegetation. It is well suited for larger treatment areas, lawn renovation and customers who prefer a professional liquid concentrate.

Weed and Grass Killer

Frequently Asked Questions

Yes. These are non-selective herbicides and will damage and kill desirable grass. Do not spray them over turf you want to keep.

No. This collection is for products that kill both weeds and grass. For weeds growing in a lawn you want to preserve, see our full collection Weed Killer for Lawns.

Yes, provided the spray is carefully directed onto the unwanted weed. Do not let the spray contact leaves, green stems, exposed roots or other parts of desirable shrubs, flowers or trees.

Glyphosate has no soil activity and does not control grass seed placed into the soil. However, you should follow the product label and allow enough time for the herbicide to move through the existing vegetation before mowing, tilling or beginning lawn renovation.

Visible results vary by product, weed type, temperature and growing conditions. Round-up Quickpro will show symptoms sooner, while complete control of established perennial weeds and grasses can take 7-14 days.

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